Adsorptive Hemodialysis Membrane for Creatinine Removal

Saiful Saiful, Maya Rizki Imanda, Lidya Mardiana, Khairi Khairi, Rahmi Rahmi, Yanuardi Raharjo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)


Blood purification is essential in the medical field to separate and eliminate toxins and impurities in the bloodstream. To eliminate all the toxic substances in the body, the hemodialysis membrane must have adsorption properties to adsorb all the toxins that cannot be removed by diffusion through the membrane pore. A hemodialysis membrane of chitosan starch without crosslinking and crosslinking has been made to separate creatinine compounds. Chitosan-starch crosslink membranes are made using glutaraldehyde as a crosslinking agent. Chitosan-starch membrane without crosslinking has a tensile strength of l0.07 kgf/mm2, while the membrane of crosslinked chitosan has a better tensile strength of 66.79 kgf/mm2. The chitosan-starch membrane without crosslinking has clean water fluxes of 9l, 60 L/m2 hour, while the chitosan-starch membrane crosslinking has water fluxes of 89.l7 L/m2 hour. Chitosan-starch membrane without crosslinking can remove creatinine of 6.427 mg Crt/gram membrane where the amount removed by adsorption reaches 3.828 mg Crt/g membrane. Chitosan-starch crosslinked membrane can remove creatinine of 5,682 mg Crtgram membrane with the amount removed by adsorption reaching 3.589 mgCrt/gram membrane. Chitosan-starch hemodialysis membranes can remove creatinine through a combination of adsorption and diffusion in one step.

Original languageEnglish
Title of host publication8th International Conference and Workshop on Basic and Applied Science, ICOWOBAS 2021
EditorsAnjar Tri Wibowo, M. Fariz Fadillah Mardianto, Riries Rulaningtyas, Satya Candra Wibawa Sakti, Muhammad Fauzul Imron, Rico Ramadhan
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735442610
Publication statusPublished - 25 Jan 2022
Event8th International Conference and Workshop on Basic and Applied Science, ICOWOBAS 2021 - Surabaya, Indonesia
Duration: 25 Aug 202126 Aug 2021

Publication series

NameAIP Conference Proceedings
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616


Conference8th International Conference and Workshop on Basic and Applied Science, ICOWOBAS 2021


Dive into the research topics of 'Adsorptive Hemodialysis Membrane for Creatinine Removal'. Together they form a unique fingerprint.

Cite this