Abstract

The aim was determine the effi cacy of Syzygium cumini leaf and fruit extracts nanoparticles to mice infected with Plasmodium berghei at 1×105 of Plasmodium berghei. Treatment was given 24 hours post infection for 4 days. Observed from the 5th day to 12th day post infection. The results of per cent parasitemia, growth inhibition, Parasite Clearance Time, and Recrudescence Time of parasites. Syzygium cumini fruit nanoparticles with chloroquine were better than Syzygium cumini leaf nanoparticles with chloroquine, whereas the Survival time, Hb content, splenic index and liver index were same. Effi cacy of Syzygium cumini leaf and fruit extracts nanoparticles increased when used as an adjuvant therapy with chloroquin in mice infected by Plasmodium berghei.

Original languageEnglish
Pages (from-to)33-36
Number of pages4
JournalIndian Veterinary Journal
Volume97
Issue number2
Publication statusPublished - 2020

Keywords

  • Nanoparticle
  • Plasmodium berghei
  • Syzygium cumini
  • Therapy

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