Acute pseudomembranous candidiasis accompanied with oral malignant lesions in HIV-Infected Patient

Objective: Oral candidiasis is the most opportunistic infection in HIV/AIDS patient. Neoplasms may also frequently be found in the oral cavity of HIV/AIDS patient and may indicate the progression of HIV infection. Methods: A 56-year-old complaint of yellowish-white spots in oral cavity and swelling in the palate accompanied with shortness of breath and difficulty in eating and swallowing. Various medication was used to relieve the complaints but there were no improvements. He claimed a weight loss of 10 kg in last three months. Physically showed pale and weakness. Intraorally, diffuse pseudomembranous was found throughout the oral cavity to pharynx, and an exophytic mass with red color at the palate area extending to oropharynx. Direct mycology test, complete blood count examination and HIV rapid test were conducted. Results: Topical antifungal and antiseptic mouthwash was prescribed after direct mycology test result was positive for Candida albicans, a reactive anti-HIV examination with immunochromatography confirmed the patients was HIV and referral to head and neck oncologist for the Kaposi’s sarcoma. In second visit, two days after therapy, the pseudomembrane slightly reduced, but complaints of tightness still felt. Unfortunately, the patients passed away after second visit and have not yet received therapy from head and neck oncologist. Conclusion: Oral candidiasis may be the oral manifestation of HIV/AIDS which may accompanied by oral malignant lesions. Due to the late management of the oral candidiasis and oral malignant lesion, may result in poor prognosis for the treatment of the patient.