Acute Effects of Interval and Continuous Physical Activity with Moderate Intensity on Biomarker Bone Formation Procollagen Amino Terminal Propeptide and Bone Carboxy-Terminal Crosslink Telepoptide

Gadis Meinar Sari, Yanuar Alfan Triardhana, Paulus Liben

Research output: Contribution to journalArticlepeer-review

Abstract

Physical activity can affect the bone remodeling process and has an impact on bone health. The bone remodeling through a coupling process consisting of formation and reabsorption. The process stimulates molecules to release collagen into the circulation, i.e., P1NP (osteoblast marker) and CTx (osteoclast marker). However, the acute effect of continous and interval physical activity at moderate intensity on P1NP and CTx has not been recognized yet. This study aims to analyze the disparity of acute effects caused by intervals and continous physical activity with moderate intensity during the growth period of the bone. This study uses a pre-test and post-test design experimental study. The total sample is 16 which were divided into two groups (interval physical activity group and continous physical activity group). There was no acute effect on the moderate intensity of continous physical activity on P1NP (p=0.759), but it has shown a decline. Likewise, moderate intensity of acute interval physical activity has shown no effect on P1NP (p=0.013). This phenomenon happened in the moderate intensity of continous physical activity on CTx (p=0.173), as well as the moderate intensity of interval physical activity on CTx (p=0.693). The study revealed no difference in the acute effect of continous and interval physical activity with moderate intensity on P1NP (p=0.209) and CTx (p=0.164). The acute effect of interval physical activity on moderate-intensity can decrease P1NP levels.

Original languageEnglish
Pages (from-to)124-130
Number of pages7
JournalJournal of International Dental and Medical Research
Volume16
Issue number1
Publication statusPublished - 2023

Keywords

  • Bone remodelling
  • CTx
  • P1NP
  • interval and continuous physical activity
  • medicine
  • moderateintensity

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