@inproceedings{9c87da7129b1430e9a9b732525d82f49,
title = "A two-dimensional simulation of plasma leakage due to dengue infection",
abstract = "Dengue Hemorrhagic Fever (DHF) is a disease caused by Dengue virus infection. One major characteristic in a patient with DHF is the occurrence of plasma leakage. Plasma leakage is a consequence of the immune system mechanism which activates cytokine. As a result, permeability of vascular will increase. Another characteristic in a DHF patient is hypoalbuminea (decreasing of albumin concentration). Plasma leakage can be modelled by constructing mathematical model of albumin concentration in plasma blood due to increasing of cytokine. In this paper, decreasing of albumin concentration in blood plasma is modelled using diffusion equation. In addition, two-dimensional numerical simulations of albumin concentration are also presented. From the simulation, it is found that the greater leakage rate or the wider leakage area, the greater decreasing albumin concentration will be. Furthermore, when time t increases, the albumin concentration decreases to zero.",
keywords = "albumin, diffusion equation, hypoalbuminemia, mathematical model, plasma leakage",
author = "Nuning Nuraini and Windarto and Swarna Jayanti and Edy Soewono",
year = "2014",
doi = "10.1063/1.4868839",
language = "English",
isbn = "9780735412217",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
pages = "444--447",
booktitle = "4th International Conference on Mathematics and Natural Sciences, ICMNS 2012",
note = "4th International Conference on Mathematics and Natural Sciences: Science for Health, Food and Sustainable Energy, ICMNS 2012 ; Conference date: 08-11-2012 Through 09-11-2012",
}
