A review on pulmonary and mediastinal synovial sarcoma

Kristin Purnama Dewi, Ivana Purnama Dewi, Iswanto Iswanto, Laksmi Wulandari

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)

Abstract

Sarcoma is defined as a tumor located in the thoracic cavity. However, sarcoma can occur on every side of the body. Synovial sarcoma is a rare soft tissue tumor originating from pluripotent with a high malignancy rate. The most common predilection of synovial sarcoma is in the joints. Primary synovial sarcoma of the lung and mediastinum are rare tumors and generally malignant. There are only a few cases have been reported. Definite diagnosis is made by histopathological, immunohistochemistry, and cytogenetic examination. The management strategy for synovial sarcoma requires multimodality treatment with surgery, chemotherapy, and radiotherapy. However, effective and relatively non-toxic therapy for primary synovial sarcoma is still developed. The five years life expectancy is higher if the patient received adjuvant radiotherapy and/or chemotherapy after surgery.

Original languageEnglish
Pages (from-to)169-175
Number of pages7
JournalJournal of Basic and Clinical Physiology and Pharmacology
Volume34
Issue number2
DOIs
Publication statusPublished - 1 Mar 2023

Keywords

  • mediastinum
  • pulmonary
  • review
  • synovial sarcoma

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