A Review of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) on Bovine Mastitis

Aswin Rafif Khairullah, Sancaka Cashyer Ramandinianto, Mustofa Helmi Effendi

Research output: Contribution to journalReview articlepeer-review

19 Citations (Scopus)


Bovine mastitis is a disease in dairy cows that can cause productivity losses in the form of decreased quality and quantity of milk production. Staphylococcus aureus is the main pathogenic bacterium among a variety of bacteria that are responsible for mastitis cases in dairy cows. Staphylococcus aureus which is resistant to methicillin or known as Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to most β-lactam antibiotics. Livestock associated-methicillin-resistant Staphylococcus aureus (LA-MRSA) is a global threat to the health of livestock and humans. This bacterial strain is responsible for a variety of diseases ranging from superficial skin infections to life-threatening diseases. LA-MRSA isolates from both animals and humans are sensitive to vancomycin antibiotics. In addition, LA-MRSA isolates were also sensitive to linezolid, amikacin, and teicoplanin. Prevention of LA-MRSA transmission can be done by improving the biosecurity and environmental cleanliness of dairy cattle pens, as well as regulating animal and human health care regularly.

Original languageEnglish
Pages (from-to)172-183
Number of pages12
JournalSystematic Reviews in Pharmacy
Issue number7
Publication statusPublished - Aug 2020


  • Antibiotics resistance
  • Bovine mastitis
  • Human health


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