A primary biomarker examination in preventing progressivity of acute respiratory distress syndrome: The role of surfactant protein-d in sepsis induced ARDS

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Sepsis is one of the most unreachable conditions of hospitalization and a major contributor to hospital mortality, representing a major worldwide health burden. Sepsis is a syndrome characterized by an irregular host response to pathogens invasion, which involving hemodynamic changes that lead to multiple lifethreatening organ dysfunctions. Among the injured organs, the lung is the first and most frequent organ to fail. Acute respiratory dis. tress syndrome (ARDS) develops with many serious medical disorders. At least, mortality is 40% and there is no specific therapy. ARDS is an acute inflammatory process in the lung caused by infection direct or indirectly to the alveolar-capillary membrane. Currently, ARDS is diagnosed based on a combination of clinical and physiological variables. In this article, we will review the current understanding of surfactant protein-D as one of many biomarkers in ARDS diagnosis.

Original languageEnglish
Pages (from-to)65-75
Number of pages11
JournalCritical Care and Shock
Volume23
Issue number2
Publication statusPublished - 2020
Externally publishedYes

Keywords

  • ARDS
  • ARDS biomarker
  • Blood biomarker
  • Sepsis induced ARDS
  • Surfactant protein-D

Fingerprint

Dive into the research topics of 'A primary biomarker examination in preventing progressivity of acute respiratory distress syndrome: The role of surfactant protein-d in sepsis induced ARDS'. Together they form a unique fingerprint.

Cite this