A new havanensin-type limonoid from Chisocheton macrophyllus

Nurlelasari, Intan Rahmayanti, Supriatno Salam, Agus Safari, Desi Harneti, Rani Maharani, Ace Tatang Hidayat, Mulyadi Tanjung, Rurini Retnowati, Yoshihito Shiono, Unang Supratman

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


A new havanensin-type limonoid, 16β-hydroxydysobinin (1), along with four known limonoids (2–5), have been isolated from the seeds of Chisocheton macrophyllus. The chemical structure of the new compound was determined by referencing spectroscopic data, and by comparison to those related spectra previously reported. Each compound was evaluated for their cytotoxic effects against Michigan Cancer Foundation-7 (MCF-7) breast cancer cells and display no significant activity.

Original languageEnglish
Article number35
JournalApplied Biological Chemistry
Issue number1
Publication statusPublished - Dec 2021


  • 16β-hydroxydysobinin
  • Chisocheton macrophyllus
  • Limonoid
  • MCF-7
  • Meliaceae


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