TY - JOUR
T1 - A comprehensive review of the effects of porosity and macro- and micropore formations in porous β-TCP scaffolds on cell responses
AU - Mohammed Mohammed, Ahmed Hafedh
AU - Shariff, Khairul Anuar
AU - Wahjuningrum, Dian Agustin
AU - Bakar, Mohamad Hafizi Abu
AU - Mohamad, Hasmaliza
N1 - Publisher Copyright:
© 2023, The Author(s) under exclusive licence to Australian Ceramic Society.
PY - 2023/9
Y1 - 2023/9
N2 - The present study comprehensively reviewed the effects of porosity, micropores, and macropores of porous β-TCP scaffold on cell responses. Relevant information from reports conducted between 2000 and 2022 available in databases, such as ScienceDirect, Google Scholar, Scopus, and PubMed, were systematically searched during this study. Although numerous studies have reported on porous β-TCP scaffolds, no publication has discussed the effects of porosity and micropore and macropore formations in porous β-TCP scaffolds towards cell response. Consequently, the current review presented a comprehensive understanding of the roles of porosity and macro- and micropore sizes in influencing cell activities towards porous β-TCP scaffolds. The information discussed in this review would provide new insights into the significance of porosity, macropores, and micropores in inducing bone-like cell activities towards porous β-TCP scaffolds.
AB - The present study comprehensively reviewed the effects of porosity, micropores, and macropores of porous β-TCP scaffold on cell responses. Relevant information from reports conducted between 2000 and 2022 available in databases, such as ScienceDirect, Google Scholar, Scopus, and PubMed, were systematically searched during this study. Although numerous studies have reported on porous β-TCP scaffolds, no publication has discussed the effects of porosity and micropore and macropore formations in porous β-TCP scaffolds towards cell response. Consequently, the current review presented a comprehensive understanding of the roles of porosity and macro- and micropore sizes in influencing cell activities towards porous β-TCP scaffolds. The information discussed in this review would provide new insights into the significance of porosity, macropores, and micropores in inducing bone-like cell activities towards porous β-TCP scaffolds.
KW - Bioceramic
KW - Bone remodelling
KW - Calcium phosphate
KW - Ceramic coating
KW - Porous β-TCP scaffold
UR - http://www.scopus.com/inward/record.url?scp=85152711809&partnerID=8YFLogxK
U2 - 10.1007/s41779-023-00880-0
DO - 10.1007/s41779-023-00880-0
M3 - Article
AN - SCOPUS:85152711809
SN - 2510-1560
VL - 59
SP - 865
EP - 879
JO - Journal of the Australian Ceramic Society
JF - Journal of the Australian Ceramic Society
IS - 4
ER -