TY - JOUR
T1 - A comprehensive review of recent advances in the applications and biosynthesis of oxalic acid from bio-derived substrates
AU - Amenaghawon, Andrew Nosakhare
AU - Ayere, Joshua Efosa
AU - Amune, Ubani Oluwaseun
AU - Otuya, Ifechukwude Christopher
AU - Abuga, Emmanuel Christopher
AU - Anyalewechi, Chinedu Lewis
AU - Okoro, Oseweuba Valentine
AU - Okolie, Jude A.
AU - Oyefolu, Peter Kayode
AU - Eshiemogie, Steve Oshiokhai
AU - Osahon, Blessing Esohe
AU - Omede, Melissa
AU - Eshiemogie, Stanley Aimhanesi
AU - Igemhokhai, Shedrach
AU - Okedi, Maxwell Ogaga
AU - Kusuma, Heri Septya
AU - Muojama, Obiora Ebuka
AU - Shavandi, Amin
AU - Darmokoesoemo, Handoko
N1 - Publisher Copyright:
© 2024 Elsevier Inc.
PY - 2024/6/15
Y1 - 2024/6/15
N2 - Organic acids are important compounds with numerous applications in different industries. This work presents a comprehensive review of the biological synthesis of oxalic acid, an important organic acid with many industrial applications. Due to its important applications in pharmaceuticals, textiles, metal recovery, and chemical and metallurgical industries, the global demand for oxalic acid has increased. As a result, there is an increasing need to develop more environmentally friendly and economically attractive alternatives to chemical synthesis methods, which has led to an increased focus on microbial fermentation processes. This review discusses the specific strategies for microbial production of oxalic acid, focusing on the benefits of using bio-derived substrates to improve the economics of the process and promote a circular economy in comparison with chemical synthesis. This review provides a comprehensive analysis of the various fermentation methods, fermenting microorganisms, and the biochemistry of oxalic acid production. It also highlights key sustainability challenges and considerations related to oxalic acid biosynthesis, providing important direction for further research. By providing and critically analyzing the most recent information in the literature, this review serves as a comprehensive resource for understanding the biosynthesis of oxalic acid, addressing critical research gaps, and future advances in the field.
AB - Organic acids are important compounds with numerous applications in different industries. This work presents a comprehensive review of the biological synthesis of oxalic acid, an important organic acid with many industrial applications. Due to its important applications in pharmaceuticals, textiles, metal recovery, and chemical and metallurgical industries, the global demand for oxalic acid has increased. As a result, there is an increasing need to develop more environmentally friendly and economically attractive alternatives to chemical synthesis methods, which has led to an increased focus on microbial fermentation processes. This review discusses the specific strategies for microbial production of oxalic acid, focusing on the benefits of using bio-derived substrates to improve the economics of the process and promote a circular economy in comparison with chemical synthesis. This review provides a comprehensive analysis of the various fermentation methods, fermenting microorganisms, and the biochemistry of oxalic acid production. It also highlights key sustainability challenges and considerations related to oxalic acid biosynthesis, providing important direction for further research. By providing and critically analyzing the most recent information in the literature, this review serves as a comprehensive resource for understanding the biosynthesis of oxalic acid, addressing critical research gaps, and future advances in the field.
KW - Bacteria
KW - Fermentation
KW - Fungi
KW - Microorganism
KW - Organic acid
KW - Oxalic acid
UR - http://www.scopus.com/inward/record.url?scp=85188749206&partnerID=8YFLogxK
U2 - 10.1016/j.envres.2024.118703
DO - 10.1016/j.envres.2024.118703
M3 - Review article
C2 - 38518912
AN - SCOPUS:85188749206
SN - 0013-9351
VL - 251
JO - Environmental Research
JF - Environmental Research
M1 - 118703
ER -