TY - JOUR
T1 - A comprehensive review of paratuberculosis in animals and its implications for public health
AU - Meles, Dewa Ketut
AU - Mustofa, Imam
AU - Khairullah, Aswin Rafif
AU - Wurlina, Wurlina
AU - Mustofa, Rheza Imawan
AU - Suwasanti, Niluh
AU - Akintunde, Adeyinka Oye
AU - Putra, Satriawan Wedniyanto
AU - Kusala, Muhammad Khaliim Jati
AU - Moses, Ikechukwu Benjamin
AU - Wibowo, Syahputra
AU - Raissa, Ricadonna
AU - Fauzia, Kartika Afrida
AU - Abdila, Syafiadi Rizki
AU - Yanestria, Sheila Marty
AU - Fauziah, Ima
N1 - Publisher Copyright:
© 2024, Faculty of Veterinary Medicine, University of Tripoli. All rights reserved.
PY - 2024
Y1 - 2024
N2 - Paratuberculosis is an infectious disease caused by Mycobacterium avium subspecies paratuberculosis (MAP). Typically, ruminant animals including cattle, buffalo, goats, and sheep are infected with MAP. Animals get infected with MAP in a number of ways, such as by eating or drinking contaminated food or water, or by nursing from an infected mother who may have contaminated teats or directly shed the organism in milk or colostrum. Animal-derived goods like meat, dairy, and tainted surface water have the potential to spread paratuberculosis through zoonotic transmission. Reports of paratuberculosis have been received from United States, Oceania, Asia, and Africa, in addition to several European nations like Germany, Italy, and France. Paratuberculosis pathology is characterized by chronic lymphangitis, chronic enteritis, or mesenteric lymphadenopathy. In animals, wasting and watery green diarrhea are the major signs. There are two kinds of paratuberculosis diagnostic tests that are available; the goal of the first set of tests is to identify MAP while the second set consists of immunological tests. Due to similar clinical signs, some forms of the illness, such as wasting and watery green diarrhea, may be mistaken for paratuberculosis. Crohn’s disease has been linked to M. avium subsp. paratuberculosis as the etiological culprit in humans. To prevent the infection from spreading to uninfected animal populations, drastic measures must be implemented. Despite the economic burden of paratuberculosis, research aimed at developing therapeutic medicines is focused on public health rather than veterinary uses. This review therefore focuses on a comprehensive detail of paratuberculosis in animals, including its public health implications and economic impact.
AB - Paratuberculosis is an infectious disease caused by Mycobacterium avium subspecies paratuberculosis (MAP). Typically, ruminant animals including cattle, buffalo, goats, and sheep are infected with MAP. Animals get infected with MAP in a number of ways, such as by eating or drinking contaminated food or water, or by nursing from an infected mother who may have contaminated teats or directly shed the organism in milk or colostrum. Animal-derived goods like meat, dairy, and tainted surface water have the potential to spread paratuberculosis through zoonotic transmission. Reports of paratuberculosis have been received from United States, Oceania, Asia, and Africa, in addition to several European nations like Germany, Italy, and France. Paratuberculosis pathology is characterized by chronic lymphangitis, chronic enteritis, or mesenteric lymphadenopathy. In animals, wasting and watery green diarrhea are the major signs. There are two kinds of paratuberculosis diagnostic tests that are available; the goal of the first set of tests is to identify MAP while the second set consists of immunological tests. Due to similar clinical signs, some forms of the illness, such as wasting and watery green diarrhea, may be mistaken for paratuberculosis. Crohn’s disease has been linked to M. avium subsp. paratuberculosis as the etiological culprit in humans. To prevent the infection from spreading to uninfected animal populations, drastic measures must be implemented. Despite the economic burden of paratuberculosis, research aimed at developing therapeutic medicines is focused on public health rather than veterinary uses. This review therefore focuses on a comprehensive detail of paratuberculosis in animals, including its public health implications and economic impact.
KW - Diarrhea
KW - Intestines
KW - MAP
KW - Paratuberculosis
KW - Public health
UR - http://www.scopus.com/inward/record.url?scp=85211644907&partnerID=8YFLogxK
U2 - 10.5455/OVJ.2024.v14.i11.2
DO - 10.5455/OVJ.2024.v14.i11.2
M3 - Review article
AN - SCOPUS:85211644907
SN - 2226-4485
VL - 14
SP - 2731
EP - 2744
JO - Open Veterinary Journal
JF - Open Veterinary Journal
IS - 11
ER -