TY - GEN
T1 - 3D virtual intravascular endoscopy visualization of coronary artery plaques
T2 - 3rd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2009
AU - Sun, Zhonghua
AU - Chaichana, Thanapong
AU - Dimpudus, Franky Jacobus
AU - Adipranoto, Jeffrey Daniel
AU - Nugroho, Johanes
PY - 2009
Y1 - 2009
N2 - The purpose of the study is to investigate the potential diagnostic value of 3D virtual intravascular endoscopy in the visualization of coronary artery plaques in patients with suspected coronary artery disease. Ten patients suspected of coronary artery disease undergoing 64-slice computed tomography scans were included in the study. Four main coronary artery branches including right coronary artery, left main stem, left anterior descending and left circumflex were assessed using virtual intravascular endoscopy with emphasis on the intraluminal appearance of coronary plaques (calcified and noncalcified plaques). Position of the plaques and degree of vessel stenosis was compared with 2D axial images in each patient. Coronary artery disease with >50% stenosis was found in 6 patients involving 7 left anterior descending and 3 right coronary artery branches. Left anterior descending branch was commonly affected with extensive calcification, while more than half of the right coronary arteries were involved with noncalcified plaques. Our results showed that virtual intravascular endoscopy provides unique information of the coronary plaques by demonstrating the intraluminal configuration of coronary plaques, position of the plaques in relation to the artery branches. Both calcified and noncalcified plaques can be identified on virtual endoscopy images. Further studies are needed to clarify the role of virtual intravascular endoscopy in the quantification of plaque volume, stratification of patients suffering from coronary artery disease and patients management.
AB - The purpose of the study is to investigate the potential diagnostic value of 3D virtual intravascular endoscopy in the visualization of coronary artery plaques in patients with suspected coronary artery disease. Ten patients suspected of coronary artery disease undergoing 64-slice computed tomography scans were included in the study. Four main coronary artery branches including right coronary artery, left main stem, left anterior descending and left circumflex were assessed using virtual intravascular endoscopy with emphasis on the intraluminal appearance of coronary plaques (calcified and noncalcified plaques). Position of the plaques and degree of vessel stenosis was compared with 2D axial images in each patient. Coronary artery disease with >50% stenosis was found in 6 patients involving 7 left anterior descending and 3 right coronary artery branches. Left anterior descending branch was commonly affected with extensive calcification, while more than half of the right coronary arteries were involved with noncalcified plaques. Our results showed that virtual intravascular endoscopy provides unique information of the coronary plaques by demonstrating the intraluminal configuration of coronary plaques, position of the plaques in relation to the artery branches. Both calcified and noncalcified plaques can be identified on virtual endoscopy images. Further studies are needed to clarify the role of virtual intravascular endoscopy in the quantification of plaque volume, stratification of patients suffering from coronary artery disease and patients management.
KW - Calcification
KW - Computed tomography
KW - Coronary artery disease
KW - Plaque
KW - Virtual intravascular endoscopy
UR - http://www.scopus.com/inward/record.url?scp=72749110257&partnerID=8YFLogxK
U2 - 10.1109/ICBBE.2009.5162142
DO - 10.1109/ICBBE.2009.5162142
M3 - Conference contribution
AN - SCOPUS:72749110257
SN - 9781424429028
T3 - 3rd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2009
BT - 3rd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2009
Y2 - 11 June 2009 through 13 June 2009
ER -
